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2026 (Current Year) Faculty Courses School of Life Science and Technology Undergraduate major in Life Science and Technology

Animal Physiology

Academic unit or major
Undergraduate major in Life Science and Technology
Instructor(s)
Nobuhiro Nakamura / Nobuaki Shiraki / Yoh-Ichi Tagawa / Kumi Kuroda
Class Format
Lecture (Face-to-face)
Media-enhanced courses
-
Day of week/Period
(Classrooms)
7-8 Mon (M-178(H1101)) / 7-8 Thu (M-178(H1101))
Class
-
Course Code
LST.A344
Number of credits
200
Course offered
2026
Offered quarter
2Q
Syllabus updated
Mar 18, 2026
Language
Japanese

Syllabus

Course overview and goals

Animal physiology is the science that seeks to explain the physical and chemical mechanisms that are responsible for the origin, development, and progression of life, and is fundamental to understanding human health and disease.
This course aims to help students understand the basic concepts and mechanisms of how multicellular animals maintain homeostasis through various organ systems, such as the cardiovascular and digestive systems. This course also aims for students to understand molecular mechanisms of 1) the endocrine system that detects and responses to changes in internal environment of the body and 2) the immune system that recognizes and eliminates foreign substances and organisms, such as pathogens.

Course description and aims

At the end of this course, students will be able to:
1) Understand the functions of organ systems and tissue homeostasis in animals.
2) Explain endocrine regulation of homeostasis and its signaling mechanisms.
3) Explain the basic concepts of the immunological defense system.

Keywords

Homeostasis, Cardiovascular system, Digestive systems, Immunology, Endocrine, Metabolism

Competencies

  • Specialist skills
  • Intercultural skills
  • Communication skills
  • Critical thinking skills
  • Practical and/or problem-solving skills

Class flow

Students may be given written tests or reports. The score of tests/reports will be used for academic assessment.

Course schedule/Objectives

Course schedule Objectives
Class 1

The basics of animal physiology (Kuroda)

Students can explain the animal body system, spanning from cells, tissues, to organs, as well as the homeostatic regulation.
Preparation and review of the lecture are strongly recommended.

Class 2

The cardiovascular system (Kuroda)

Students can explain the basics about the cardiovascular system, its functions and research methodologies.
Preparation and review of the lecture are strongly recommended.

Class 3

What is the endocrine system? Endocrine system vs. nervous system (Shiraki)

Students can explain basic issues of the endocrine system. Preparation and review of the textbook are strongly recommended.

Class 4

Hormones, receptors, and signal transduction (Shiraki)

Students can explain the relationship between the hormone and hormone receptors and hormone-mediated signal transduction. Preparation and review of the textbook are strongly recommended.

Class 5

Hormones, receptors, and signal transduction (Shiraki)

Students can explain stress-induced hormone secretion and hormone-mediated glucose metabolism. Preparation and review of the textbook are strongly recommended.

Class 6

Physiological roles of hormones (2): Body fluid regulation

Students can explain the mechanisms of body fluids regulation through the renin-angiotensin-aldosterone system. Preparation and review of the textbook are strongly recommended.

Class 7

The digestive system (Kuroda)

Students can explain the basics about the digestive system and the relevant metabolic system. Preparation and review of the lecture are strongly recommended.

Class 8

Other organ systems (Kuroda)

Students can explain the basics about the other organ systems such as respiratory, urinary, reproductive systems. Preparation and review of the lecture are strongly recommended.

Class 9

Mid-term examination (class #1-8)

Evaluate the understanding of Classes 1-8. Review of the lectures is strongly recommended.

Class 10

The mechanism of generating antibody diversity (Nakamura)

Students can explain the mechanism of antibody diversity (immunoglobulins).
Preparation and review of the textbook (chapter 25) is strongly recommended.

Class 11

Infection and inflammation (Tagawa)

Students can explain infections of microbes, including viruses, bacteria and
parasites, and the inflammation caused by these infections. Preparation and review of the textbook are strongly recommended.

Class 12

Innate and acquired immunity (Tagawa)

Students can explain innate and acquired immunity, which is the host's defense
against infection. Preparation and review of the textbook are strongly recommended.

Class 13

Immunological studies using developmental engineering technology (Tagawa)

Students can explain immunological studies using transgenic and gene knockout animals.
Preparation and review of the textbook are strongly recommended.

Class 14

Animal models of autoimmune diseases & Examination (Tagawa)

Students can explain autoimmune disease studies using their model animals.
Preparation and review of the textbook are strongly recommended.
Evaluate the understanding of Classes 11-14.

Study advice (preparation and review)

To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterwards (including assignments) for each class.
They should do so by referring to textbooks and other course material.

Textbook(s)

(Shiraki) Donald Voet, Judith G.Voet, BIOCHEMISTRY (Tokyo Kagaku Dozin) Part 16-19, ISBN978-4-8079-0807-3
(Nakamura, Tagawa)Bruce Albert et al., Molecular Biology of the Cell, 5th Edition (Newton Press) Chapter 24-25, ISBN978-4-315-
51867-2

Reference books, course materials, etc.

Course materials will be provided during class or through LMS as the need arises.
(Shiraki) Kazuwa Nakano 『SAISHIN NAIBUNPITSUTAISHYAGAKU』 (SHINDAN TO CHIRYO SHA) (in Japanease), ISBN978-4-7878-1937-6
(Nakamura, Tagawa)『JANEWAY'S Immunobiology』 Nankodo

Evaluation methods and criteria

Academic assessment will be done by the scores of written tests and/or reports.
In cases of plagiarism, unauthorized use, or other misconduct, we will treat it strictly.

Related courses

  • LST.A208 : Molecular Biology I
  • LST.A335 : Molecular Genetics
  • LST.A362 : Evolution and Developmental Biology
  • LST.A346 : Basic Neuroscience
  • LST.A406 : Molecular Developmental Biology and Evolution
  • LST.A401 : Molecular and Cellular Biology
  • LST.A404 : Cell Physiology
  • LST.A213 : Molecular Biology II
  • LST.A352 : Cell Engineering
  • LST.A421 : Functional Life Science

Prerequisites

Student are recommended to complete classes of 6Q and 7Q, Molecular biology 1 and 2, and 9Q Genetics.