2025 (Current Year) Faculty Courses School of Science Department of Chemistry Graduate major in Chemistry
Advanced Separation Science
- Academic unit or major
- Graduate major in Chemistry
- Instructor(s)
- Akihide Hibara / Gaku Fukuhara
- Class Format
- Lecture
- Media-enhanced courses
- -
- Day of week/Period
(Classrooms) - Class
- -
- Course Code
- CHM.B431
- Number of credits
- 200
- Course offered
- 2025
- Offered quarter
- 3Q
- Syllabus updated
- Mar 19, 2025
- Language
- English
Syllabus
Course overview and goals
This course teaches the fundamentals of separation required in various chemical studies. Molecular mechanisms that separation relies on, quantitative interpretation of separation processes, what causes good or poor separation etc will be theoretically considered based on physical phenomena including fluid mechanics and mass transfer as well as chemical interactions. This course enables students to overcome the problems that they will encounter in their own research work.
Course description and aims
By the end of this course, students will: 1. Know physics and chemistry involved in separation processes. 2. Understand the quantitative interpretation of results of separation. 3. Know dynamics and statics of separation processes. 4. Know how to improve separation performance. 5. Know that separation is not only a practical tool but also an efficient probe to the solution and interfacial phenomena
Keywords
Two-phase distribution, Chromatography, Fluid mechanics, Electrostatic theory
Competencies
- Specialist skills
- Intercultural skills
- Communication skills
- Critical thinking skills
- Practical and/or problem-solving skills
Class flow
Students should answer exercise quiz related to the lecture during each class.
Course schedule/Objectives
| Course schedule | Objectives | |
|---|---|---|
| Class 1 | Molecular distribution in two phase systems | Understand two phase distribution. |
| Class 2 | Fundamentals of chromatography | Understand fundamentals of chromatography. |
| Class 3 | Parameters in chromatographic separation | Understand quantitative description of chromatography with physical and chemical parameters. |
| Class 4 | Characteristics of fluid flow | Understand fluid flow based on fluid mechanics. |
| Class 5 | Diffusion and mass transport | Understand diffusion and mass transport. |
| Class 6 | Electrostatic interpretation of ion exchange | Interpret ion exchange phenomena based on electrostatic theory. |
| Class 7 | Electrohporesis | Introduce principle of electrophoresis. |
| Class 8 | Weak interactions on separation | Understand weak interactions on separation. |
| Class 9 | Cooperativity on separation | Understand effects on how cooperativity can be operative. |
| Class 10 | Allosterism on separation | Understand allosterism which can apply to separation. |
| Class 11 | Thermodynamics on separation | Understand advance thermodynamics which can apply to separation and analysis. |
| Class 12 | Spectroscopies for separation | Understand analyses for separated matters by means of spectroscopies. |
| Class 13 | Excited-state analytical chemistry | Understand ground- and excited-state separations. |
| Class 14 | Chirality on separation | Understand chiral chemistry on separation. |
Study advice (preparation and review)
To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterwards (including assignments) for each class.
They should do so by referring to textbooks and other course material.
Textbook(s)
None
Reference books, course materials, etc.
Course materials are provided during class.
Evaluation methods and criteria
Course scores are based on exercise quiz (100 %) .
Related courses
- CHM.B331 ： Quantitative Chemical Analysis
- CHM.B202 ： Basic Analytical Chemistry
Prerequisites
No prerequisites are necessary, but enrollment in the related courses is desirable.