2023 Faculty Courses School of Science Department of Chemistry Graduate major in Chemistry
Advanced Bioorganic Chemistry
- Academic unit or major
- Graduate major in Chemistry
- Instructor(s)
- Fumitaka Kudo
- Class Format
- Lecture (Face-to-face)
- Media-enhanced courses
- -
- Day of week/Period
(Classrooms) - 3-4 Mon (M-B43(H106)) / 3-4 Thu (M-B43(H106))
- Class
- -
- Course Code
- CHM.D431
- Number of credits
- 200
- Course offered
- 2023
- Offered quarter
- 3Q
- Syllabus updated
- Jul 8, 2025
- Language
- English
Syllabus
Course overview and goals
The student will learn how they understand and consider the biological events in living cells in terms of organic chemistry. To do so, the student will learn structures and functions of DNA, RNA, proteins, glycans, lipids based on organic chemistry. Particularly, the student will learn how low molecular weight compounds interact with the biomolecules resulting in better understanding of the biological events.
Course description and aims
The aim of the course is that the student will understand and consider the structure and function of biomolecules including DNA, RNA, proteins, glycans, polyketides, terpenoids in terms of organic chemistry. The student will understand how low molecular weight compounds interact with the biomolecules resulting in better understanding of the biological events.
Keywords
chemical biology, mode of action, interaction between biomolecules and small molecules, DNA, RNA, peptides, proteins, glycans, polyketides, terpenoids, signal transduction, receptor proteins
Competencies
- Specialist skills
- Intercultural skills
- Communication skills
- Critical thinking skills
- Practical and/or problem-solving skills
Class flow
Lectures
Course schedule/Objectives
| Course schedule | Objectives | |
|---|---|---|
| Class 1 | Introduction to bioorganic chemistry and chemical biology | Overview of chemical biology |
| Class 2 | The chemical origins of biology | Understanding of the chemical origins of biology |
| Class 3 | DNA structure and function | Understanding of DNA structure and function |
| Class 4 | DNA as a target for drugs | Understanding of DNA as a target for drugs |
| Class 5 | RNA structure and function | Understanding of RNA structure and function |
| Class 6 | Translational system as a target for drugs | Understanding of translational system as a target for drugs |
| Class 7 | Peptide and protein structure | Understanding of peptide and protein structure |
| Class 8 | Protein function | Understanding of protein function |
| Class 9 | Enzyme reactions and inhibitors | Understanding of enzyme reactions and inhibitors |
| Class 10 | Glycobiology | Understanding of glycobiology |
| Class 11 | Polyketides chemistry | Understanding of polyketides chemistry |
| Class 12 | Terpenoids | Understanding of terpenoids chemistry |
| Class 13 | Fundamental of signal transduction | Understanding of fundamental of signal transduction |
| Class 14 | Receptor proteins and small molecules in signal transduction | Understanding of receptor proteins and small molecules in signal transduction |
Study advice (preparation and review)
To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterwards (including assignments) for each class.
They should do so by referring to textbooks and other course material.
Textbook(s)
None
Reference books, course materials, etc.
”Introduction to bioorganic chemistry and chemical biology” CRC Press (Taylor & Francis Group)
related pdfs would be distributed.
Evaluation methods and criteria
Exercise problems including homework in each class (30%) and a final exam (70%)
Related courses
- CHM.D334 ： Natural Product Chemistry
- CHM.D401 ： Basic Concepts of Organic Chemistry
Prerequisites
An understanding of the fundamentals of organic chemistry is required for this course.