2022 Faculty Courses School of Materials and Chemical Technology Department of Chemical Science and Engineering Graduate major in Chemical Science and Engineering
Advanced Bioprocess Engineering
- Academic unit or major
- Graduate major in Chemical Science and Engineering
- Instructor(s)
- Mina Okochi / Masayoshi Tanaka
- Class Format
- Lecture (Livestream)
- Media-enhanced courses
- -
- Day of week/Period
(Classrooms) - 3-4 Fri
- Class
- -
- Course Code
- CAP.C425
- Number of credits
- 100
- Course offered
- 2022
- Offered quarter
- 2Q
- Syllabus updated
- Jul 10, 2025
- Language
- English
Syllabus
Course overview and goals
In biochemical reaction engineering, emphasis is placed on the use of biocatalysts in production and material transformation. An overview of recent topics on screening and breeding of biological resources, reaction kinetics of biocatalysts, bioreactor, bioseparation, genome technology and genetic engineering, biomeasurements, and environmental biotechnology is provided. Students are expected to aquire basic knowledge of biotechnology and biochemical engineering from this course.
Course description and aims
By the end of this course, students will be able to:
1) Explain characteristics of microorganisms and its cultivation conditions
2) Analyze reaction kinetics of microbial culture and bioproduct
3) Explain characteristics of enzymes and its reaction kinetics
4) Explain design and operating condition of bioreactor, and methods for separation of bioproduct
Keywords
Chemical reaction engineering, Enzymatic reaction, Microbial Fermentation, Bioseparation
Competencies
- Specialist skills
- Intercultural skills
- Communication skills
- Critical thinking skills
- Practical and/or problem-solving skills
Class flow
Required learning should be completed outside of the classroom for preparation and review purpose.
In order to deepen students' understanding of the lecture content and promote their ability to apply it, the course includes exercises, presentations, and discussions on recent topics in bioprocess engineering, as well as a report.
Course schedule/Objectives
| Course schedule | Objectives | |
|---|---|---|
| Class 1 | Introduction to Bioprocess Engineering | Overview methods for screening, storage, and breeding of microorganisms |
| Class 2 | Reaction kinetics of biocatalysts | Analyze reaction kinetics of enzymes and microorganismsreactor |
| Class 3 | Bioreactor | Understand fermentation, sterilization, control and measurements of bioreactor |
| Class 4 | Separation and purification of bioproducts | Overview bioseparation and chromatography |
| Class 5 | Genome technology and genetic engineering | Understand omics analysis, bioinformatics |
| Class 6 | Biomeasurements，Environmental biotechnology | Understand recent advancements in biochip, bio-devices, bioenergy production and wastewater treatment |
| Class 7 | Exercise problems to assess the student's level of understanding on what has been taught so far | Revise the course contents. Use the exercise problems to better understand the topics covered, and evaluate one's own progress. |
Study advice (preparation and review)
To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterwards (including assignments) for each class.
They should do so by referring to textbooks and other course material.
Textbook(s)
Course materials are provided during class
Reference books, course materials, etc.
Kenji Hashimoto. Hannou Kougaku. Tokyo: Baifukan. ISBN-10: 4563045187.
Octave Levenspiel. Chemical Reaction Engineering. Wiley, ISBN 9780471254249. Kagaku Kougakukai (Ed.) Bioproduction-Biotechnology for Bio-based Products-.Tokyo: Corona Publishing, ISBN 978-4-339-06736-1.
Kazuhisa Ohtaguchi. Reaction Engineering Analysis. Asakura Publishing. ISBN 978-4-254-25602-4.
Akihiko Kondo, Seiji Shibasaki (Eds.) Idenshi Kougaku, Kyoto: Kagakudoujin. ISBN978-4-7598-1110-0.
Evaluation methods and criteria
Exercise problems (50%), Reports (50%)
Related courses
- CAP.C206 ： Chemical Reaction Engineering I (Homogeneous System)
- CAP.C306 ： Chemical Reaction Engineering II (Heterogeneous System)
- CAP.C207 ： Introduction to Biotechnology
- CAP.C314 ： Bioprocess Engineering
- ZUJ.C301 ： Introduction to Biochemical Process
Prerequisites
None