2022 Faculty Courses School of Materials and Chemical Technology Department of Chemical Science and Engineering Graduate major in Chemical Science and Engineering
Advanced Molecular Design for Organic Synthesis II
- Academic unit or major
- Graduate major in Chemical Science and Engineering
- Instructor(s)
- Hiroshi Tanaka
- Class Format
- Lecture (Face-to-face)
- Media-enhanced courses
- -
- Day of week/Period
(Classrooms) - 3-4 Fri (S322)
- Class
- -
- Course Code
- CAP.A522
- Number of credits
- 100
- Course offered
- 2022
- Offered quarter
- 4Q
- Syllabus updated
- Jul 10, 2025
- Language
- English
Syllabus
Course overview and goals
[Summary of Lecture] In this lecture, planning of the multi-step synthesis of complex organic compounds will be explained.
[The aim of the lecture] In the synthesis of complex organic compounds, it is important to design synthetic strategy consist of multiple reactions. In this lecture, students understand synthesis unsaturated hydrocarbon and functional group transformations. In addition, student learn the synthesis of the acyclic organic molecules with several functional groups. Then, students understand the synthesis of cyclic compounds, and learn about the synthesis of bicyclic molecule that features two fused rings. Furthermore, students discuss about their designed synthetic scheme themselves. Finally, students acquire the ability to design the synthetic scheme of small organic compounds.
Course description and aims
By the end of this course, students aquire the following ability
(1) Ability to explain the synthesis of unsaturated hydrocarbons.
(2) Ability to explain the synthesis of acyclic compounds having functional groups.
(3) Ability to explain the synthesis of cyclic compounds having functional groups.
Keywords
organic synthesis, multi-step synthesis, cyclic compounds, fused ring, acyclic compounds, double bond, triple bond, oxidation, reduction.
Competencies
- Specialist skills
- Intercultural skills
- Communication skills
- Critical thinking skills
- Practical and/or problem-solving skills
Class flow
In this course, the synthesis of unsaturated compounds and hydrocarbon compounds containing a functional group transformations will be explained. Based on the knowledge, students will be asked to propose the synthesis of acyclic compounds having functional groups and discuss with the other students about it. And then, the synthesis of cyclic compounds and cyclic compound having functional groups will be explained. Based on the knowledge, students will be asked to propose the synthesis of cyclic compounds having functional groups and discuss with the other students about it. In the last day, practice problems and interpretation of them will be carried out to confirm the level of understanding.
Course schedule/Objectives
| Course schedule | Objectives | |
|---|---|---|
| Class 1 | Synthesis of saturated hydrocarbons | Explain synthesis of saturated hydrocarbons. |
| Class 2 | Transformation of functional group | Explain transformation of functional group. |
| Class 3 | Synthesis of acyclic compounds with functional groups | Explain synthesis of acyclic compounds with functional groups. |
| Class 4 | Synthesis of 5- and 6-memmered cyclic compounds | Explain synthesis of 5- and 6-memmered cyclic compounds. |
| Class 5 | Synthesis of medium sized cyclic compounds | Explain synthesis of medium sized cyclic compounds. |
| Class 6 | Synthesis of cyclic compounds with several functional groups | Explain synthesis of cyclic compounds with several functional groups. |
| Class 7 | Synthesis of complex organic compounds | Explain synthesis of complex organic compounds. |
Study advice (preparation and review)
To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterwards (including assignments) for each class.
They should do so by referring to textbooks and other course material.
Textbook(s)
undecided
Reference books, course materials, etc.
Organic Synthesis: The Disconnection Approach, 2nd Edition Wily ISBN: 978-0-470-71236-8
Evaluation methods and criteria
Term-end examination (85%), level of class participation (15%) (The level of class participation will be calculated by discussion, small examination and so on in the lecture.)
Related courses
- CAP.A521 ： Advanced Molecular Design for Organic Synthesis I
- CAP.A421 ： Advanced Design of Organic Reaction Processes I
- CAP.A422 ： Advanced Design of Organic Reaction Processes I
- CAP.T431 ： Advanced Organometallic Chemistry and Catalysis I
- CAP.T432 ： Advanced Organometallic Chemistry and Catalysis II
- CAP.A423 ： Advanced Organic Synthesis I
- CAP.A424 ： Advanced Organic Synthesis II
Prerequisites
Students should take Advanced Molecular Design for Organic Synthesis I (CAP.A521). It is desirable to study Advanced Design of Organic Reaction Processes I & II (CAP.A421・CAP.A422) or Advanced Organic Synthesis I & II (CAP.A423・CAP.A424)