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2022 Faculty Courses School of Science Department of Earth and Planetary Sciences Graduate major in Earth-Life Science

Earth-Life Science B

Academic unit or major
Graduate major in Earth-Life Science
Instructor(s)
Tomoaki Matsuura / Shawn Mcglynn / Kosuke Fujishima / Mina Okochi / Nathaniel David Virgo
Class Format
Lecture (Livestream)
Media-enhanced courses
-
Day of week/Period
(Classrooms)
1-2 Tue (ELSI-1 205) / 1-2 Fri (ELSI-1 205)
Class
-
Course Code
ELS.C402
Number of credits
200
Course offered
2022
Offered quarter
1Q
Syllabus updated
Jul 10, 2025
Language
English

Syllabus

Course overview and goals

The purpose of this class is to provide students with a wide range of fundamental knowledge in life science and related fields (molecular and cell biology, biochemical engineering, population dynamics, bioenergetics, synthetic biology, astrobiology, etc.). This class is also aimed for students who did not have the opportunity to study life science during their undergraduate period. We expect this class to provide basic knowledge towards becoming an interdisciplinary researcher through the Earth-Life Science graduate course.

Course description and aims

The goal is to learn the meanings of technical terms in fields related to life science and basic knowledge, techniques, and concepts, including laws and formulas so that students can have conversations and discussions with researchers in the same field.

Keywords

life science, molecular and cell biology, biochemical enginnering, population dynamics, bioenergetics, astrobiology, synthetic biology

Competencies

  • Specialist skills
  • Intercultural skills
  • Communication skills
  • Critical thinking skills
  • Practical and/or problem-solving skills

Class flow

The lecture will be given by five faculty members and will be delivered live via Zoom. Materials necessary for the lecture will be available for download from OCW in advance, and assignments will be given at the end of each class.

Course schedule/Objectives

Course schedule Objectives
Class 1

Introduction to life on Earth

History of biology

Class 2

Components of the cells

Biomolecules
Numbers

Class 3

Catalysis and dynamics

Enzyme catalysis
Rate equations
Diffusion and transport

Class 4

Transcription & Translation

Central dogma
Kinetic proof reading

Class 5

Synthetic Biology

Genome synthesis
Omics analysis
Synthetic cell

Class 6

Biochemical engineering

Cell growth kinetics
Clutivation control
Bioprocess

Class 7

Molecular evolution

Errors in biology
Mutagenesis amd directed evolution

Class 8

Population dynamics

Basics of population ecology
Lotka-Volterra models for predator-prey systems and competing species
Phase prortraits for dynamical systems - stability and instability, coexistence and extinction

Class 9

Evolutionary dynamics

Models of populations of replicators (Perron-Frobenius theorem)
The mutation-selection balance
Error catastrophe and "survival of the flattest"

Class 10

History and diversity of life 1

The oldest signs of life: sediments with shapes and isotopes.

Class 11

History and diversity of life 2

The molecular phylogenetic record
How are phylogenies made? Where do the data come from?
When and where did the tree of life begin?
Current views of the tree of life

Class 12

Bioenergetics of life

What is chemical energy?
All life uses electron transfer
Mechanisms of energy harvesting

Class 13

Origins of life

Different theories and models regarding the origin of life

Class 14

Life elsewhere

Habitability
Ocean worlds
Exoplanets and biosignatures

Study advice (preparation and review)

To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterwards (including assignments) for each class.
They should do so by referring to textbooks and other course material.

Textbook(s)

Essential Cell Biology, 5th International Student Edition (2018), WW Norton & Co
Astrobiology (Charles Cockell)
Evolutionary Games and Population Dynamics (Cambridge University Press)
Cell Biology by the Numbers (Garland Science)

Reference books, course materials, etc.

Each lecturer will prepare a slide and will be shared before or after the class.

Evaluation methods and criteria

Students will be graded based on class assignments and attendance record.

Related courses

  • LST.A203 : Biochemistry I
  • LST.A218 : Biochemistry II
  • LST.A208 : Molecular Biology I
  • LST.A213 : Molecular Biology II

Prerequisites

Basic