2024 Faculty Courses School of Life Science and Technology Department of Life Science and Technology Graduate major in Life Science and Technology
Medical Biotechnology
- Academic unit or major
- Graduate major in Life Science and Technology
- Instructor(s)
- Yutaka Miura / Nobuhiro Nishiyama / Yasuko Yanagida / Tetsuya Kadonosono / Kanami Orihara / Yoshiaki Masaki / Ryuji Igarashi
- Class Format
- Lecture (Livestream)
- Media-enhanced courses
- -
- Day of week/Period
(Classrooms) - 1-2 Mon / 1-2 Thu
- Class
- -
- Course Code
- LST.A504
- Number of credits
- 200
- Course offered
- 2024
- Offered quarter
- 2Q
- Syllabus updated
- Mar 14, 2025
- Language
- English
Syllabus
Course overview and goals
"Medical bioengineering" is an engineering system for developing technologies to be useful for medical use by using biotechnology techniques. Medical fields to be applied are various diseases including lifestyle diseases such as cancer. In the lecture, students learn the basics in developing materials and technologies to be applied to human beings, and also learn about diagnostic technology using imaging and biomarkers, and drug development such as regenerative medicine, biopharmaceuticals, drug delivery system, and anti-cancer drugs.
Course description and aims
Students will acquire the following knowledge by taking Medical bioengineering lectures.
1) Fundamentals of biotechnology for medical applications
2) Cancer biology and cancer therapy
3) Fundamentals and applications of biopharmaceuticals
4) Allergy and antibody
5) Fundamentals and applications of drag delivery system
6) Fundamentals and applications of biosensing
7) Fundamentals and applications of quantum sensors
Keywords
Biomaterial, Pharmacokinetics, Imaging probe, Drug delivery system, Biosensing, Quantum sensor, Lifestyle-related diseases, Allergy, Cancer, Biopharmaceuticals
Competencies
- Specialist skills
- Intercultural skills
- Communication skills
- Critical thinking skills
- Practical and/or problem-solving skills
Class flow
・The lecture will be by online (ZOOM system).
・The lecture will be carried out using PPT, and the subject quiz test will be carried out at the end of lecture.
・Please read the lecture materials distributed beforehand in T2SCHOLA and prepare.
・This lecture is all done in English, but there are cases where an overview is introduced in Japanese as necessary.
Course schedule/Objectives
| Course schedule | Objectives | |
|---|---|---|
| Class 1 | Introduction of medical biotechnology；Cancer Biology & Cancer Therapy | Learn cancer biology and therapy |
| Class 2 | Fundamentals of antibodies and their application to disease diagnosis and pharmaceuticals | Acquire knowledge of antibody-based disease diagnosis and pharmaceuticals |
| Class 3 | Fundamentals and applications of nucleic acid therapeutics | Learn mechanisms of clinically approved nucleic acid therapeutics |
| Class 4 | Design of nucleic acid therapeutics | Acquire knowledge of chemical modifications used in nucleic acid therapeutics |
| Class 5 | Pathophysiology of allergic diseases and their treatment | The basic mechanism of the pathophysiology of allergic diseases and their conventional treatment options will be explained |
| Class 6 | Applying antibody reactions to treat refractory conditions | Antibody drugs that can be used to treat refractory conditions including allergic diseases will be explained |
| Class 7 | Fundamentals and applications of biosensing technologies | Acquire knowledge about biosensing technologies |
| Class 8 | Quantum Sensors for Next-Generation Medicine: Applications in Liquid Biopsy | Gain an understanding of the next-generation ultra-early diagnosis technologies enabled by nanoscale quantum sensors |
| Class 9 | Quantum Sensors for Understanding Pathophysiology: Applications in Quantitative Microscopy Imaging | Learn how nanoscale quantum sensors enable precise measurements within the biological nano-environment |
| Class 10 | Drug delivery system for cardiovascular disease | Acquire knowledge of current status and prospect of DDS against cardiovascular diseases |
| Class 11 | Practical DDS in a pharmaceutical company | Learn about DDS in a pharmaceutical company |
| Class 12 | Design of drug delivery system (DDS) based on human body structure | Learn how to design DDS based on understanding the human body structure Learn cancer biology |
| Class 13 | DDS drug in use and clinical trials | Acquire knowledge of DDS on the market and in advanced stage of development. |
| Class 14 | Biomedical engineering in diagnosis and treatments for diseases | Understand new medical biotechnology |
Study advice (preparation and review)
To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterwards (including assignments) for each class.
They should do so by referring to textbooks and other course material.
Textbook(s)
None
Reference books, course materials, etc.
Distribute the materials at the beginning of the lecture as necessary, and explain using Power point. The power point used for the lecture is uploaded to the T2SCHOLA in advance, so use it for preparation / review.
Evaluation methods and criteria
Impose assignment quiz after each lecture. Decide the grade based on the results of the quiz. No report after lectures.
If your quiz reports are found to contain material plagiarized from literature, including the Internet, your grade will be marked zero,
Related courses
- LST.A342 ： Biomedical Materials
- LST.A352 ： Cell Engineering
- LST.A401 ： Molecular and Cellular Biology
- LST.A412 ： Biomaterial Science and Engineering
Prerequisites
Although there are no special requirements, students who take this course are required to have basic knowledge of biology / biochemistry, such as studying related subjects.