2024 Faculty Courses School of Materials and Chemical Technology Department of Chemical Science and Engineering Graduate major in Chemical Science and Engineering

Frontiers of Chemical Science and Engineering I

Academic unit or major: Graduate major in Chemical Science and Engineering
Instructor(s): Reiko Saito / Yoshiaki Shoji / Hiroyuki Isobe / Takayuki Nakamuro
Class Format: Lecture (HyFlex)
Media-enhanced courses: -
Day of week/Period (Classrooms): Intensive
Class: -
Course Code: CAP.T423
Number of credits: 100
Course offered: 2024
Offered quarter: 3-4Q
Syllabus updated: Mar 14, 2025
Language: Japanese

Syllabus

Course overview and goals

[Outline] In this lecture, we will comprehend the fundamental properties and reactivities of substances at the atomic / molecular level, advanced chemical technology systems on the design and conversion of useful substances including macromolecules, and chemistry In order to train people, researchers active at the forefront of Applied Chemistry field introduce research results from basic to applied.
[Objective] We aim to acquire a broad knowledge of researchers who are active at the forefront of applied chemistry field concerning research from basic to applied.

Course description and aims

Learn the following abilities by taking this lecture.
(1) It can explain basic properties and reactivity of substances at atomic / molecular level. (2) Explain the advanced chemical technology system on the design and conversion of useful substances. (3) Explain a wide range of knowledge from basic to applied research.

Keywords

Basic properties, atoms / molecules, materials, chemical technology, applied chemistry

Competencies

Specialist skills
Intercultural skills
Communication skills
Critical thinking skills
Practical and/or problem-solving skills

Class flow

Two lecturers will give intensive lectures in a hybrid manner with on-site and zoom for two days each. First half: Dr. Takayuki Nakamuro: Molecular Electron Microscopy Research, and second half: Dr. Hiroyuki Isobe: The Creation of Knowledge.

Course schedule/Objectives

	Course schedule	Objectives
Class 1	1-1 "Introduction to Molecular Electron Microscopy Research" Atomic resolution transmission electron microscopy (AR-TEM) achieves spatiotemporal resolutions on the order of sub-angstroms and milliseconds. This technology has the potential to become a powerful analytical tool for exploring the molecular world. This lecture will provide an overview of its development from the perspective of organic chemists. 1-2: "Recent Advances in Molecular Electron Microscopy Research" AR-TEM has demonstrated significant effectiveness in analyzing hard materials such as metals and solids. However, there have been limitations in the exploration of molecular species. This lecture will outline recent advancements in molecular electron microscopy, including electron diffraction (microED/3DED) and cryo-electron microscopy. 1-3 "Exploring Molecular Science with Atomic-Resolution Electron Microscopy" There is a notable difference between the probabilistic nature of molecules and the deterministic behavior of bulk materials. This presentation will focus on the new interpretations and prospects that AR-TEM has brought to the molecular world, discussing the latest research findings. 2-1 "The Creation of Knowledge 1: A Journey Through Physical Organic Chemistry Research" Beginning with a contemplation of what scientific research is, this lecture will review examples of modern physical organic chemistry, providing an opportunity for participants to reflect on their own research. 2-2 "The Creation of Knowledge 2: Revisiting the Foundations of Organic Chemistry" By visiting the places where the foundational knowledge of organic chemistry was created, this lecture will offer an opportunity to consider the importance of positioning one’s research in the context of past achievements. (Tokyo Institute of Technology has a tradition of lectures on the history of chemistry by the late Emeritus Professor Tatsuaki Michiya.) 2-3 "Exploring Scientific Research through Phenine-based Nanocarbon Molecules" This lecture will discuss the synthesis of nanocarbon molecules based on "phenine" and trace the new developments in modern science stemming from this research.	(1) Can explain the overview of atomic-resolution electron microscopy. (2) Can explain the recent advances in atomic-resolution electron microscopy and its exploration of molecular chemistry. (3) Can explain the creation of "knowledge" through research in physical organic chemistry. (4) Can explain the synthesis of nanocarbon molecules and the new developments in modern science.

Course schedule

Objectives

Class 1

1-1 "Introduction to Molecular Electron Microscopy Research"
Atomic resolution transmission electron microscopy (AR-TEM) achieves spatiotemporal resolutions on the order of sub-angstroms and milliseconds. This technology has the potential to become a powerful analytical tool for exploring the molecular world. This lecture will provide an overview of its development from the perspective of organic chemists.
1-2: "Recent Advances in Molecular Electron Microscopy Research"
AR-TEM has demonstrated significant effectiveness in analyzing hard materials such as metals and solids. However, there have been limitations in the exploration of molecular species. This lecture will outline recent advancements in molecular electron microscopy, including electron diffraction (microED/3DED) and cryo-electron microscopy.
1-3 "Exploring Molecular Science with Atomic-Resolution Electron Microscopy"
There is a notable difference between the probabilistic nature of molecules and the deterministic behavior of bulk materials. This presentation will focus on the new interpretations and prospects that AR-TEM has brought to the molecular world, discussing the latest research findings.

2-1 "The Creation of Knowledge 1: A Journey Through Physical Organic Chemistry Research"
Beginning with a contemplation of what scientific research is, this lecture will review examples of modern physical organic chemistry, providing an opportunity for participants to reflect on their own research.
2-2 "The Creation of Knowledge 2: Revisiting the Foundations of Organic Chemistry"
By visiting the places where the foundational knowledge of organic chemistry was created, this lecture will offer an opportunity to consider the importance of positioning one’s research in the context of past achievements. (Tokyo Institute of Technology has a tradition of lectures on the history of chemistry by the late Emeritus Professor Tatsuaki Michiya.)
2-3 "Exploring Scientific Research through Phenine-based Nanocarbon Molecules"
This lecture will discuss the synthesis of nanocarbon molecules based on "phenine" and trace the new developments in modern science stemming from this research.

(1) Can explain the overview of atomic-resolution electron microscopy.

(2) Can explain the recent advances in atomic-resolution electron microscopy and its exploration of molecular chemistry.

(3) Can explain the creation of "knowledge" through research in physical organic chemistry.

(4) Can explain the synthesis of nanocarbon molecules and the new developments in modern science.

Study advice (preparation and review)

Textbook(s)

None required.

Reference books, course materials, etc.

None

Evaluation methods and criteria

Attendance will be checked in every class. Full attendance is required in principle. Course score will be based on the reports evaluation.

Related courses

CAP.T411 ： Elements of Innovative Molecular Chemistry I
CAP.A424 ： Advanced Organic Synthesis II
CAP.A481 ： Advanced Instrumental Analysis
CAP.T412 ： Elements of Innovative Molecular Chemistry II
CAP.A521 ： Advanced Molecular Design for Organic Synthesis I
CAP.I533 ： Advanced Strategic Organic Synthesis

Prerequisites

No prerequisites.

Other

Schedule
1st lecture: November 1　(Fri), 10:45-17:05 (On-site: Ookayama, HyFlex: Suzukakedai)
2nd lecture: December 13 (Fri), 10:45-17:05 (On-site: Suzukakedai, HyFlex: Ookayama)