2024 Faculty Courses School of Materials and Chemical Technology Department of Chemical Science and Engineering Graduate major in Chemical Science and Engineering
Advanced Organometallic Chemistry and Catalysis
- Academic unit or major
- Graduate major in Chemical Science and Engineering
- Instructor(s)
- Yoshiaki Shoji
- Class Format
- Lecture (Face-to-face)
- Media-enhanced courses
- -
- Day of week/Period
(Classrooms) - 3-4 Mon
- Class
- -
- Course Code
- CAP.I439
- Number of credits
- 100
- Course offered
- 2024
- Offered quarter
- 3Q
- Syllabus updated
- Mar 14, 2025
- Language
- English
Syllabus
Course overview and goals
Organotransition metal chemistry is closely related to the mechanism of synthetic organic reaction as well as of polymer synthesis from olefins using transition metal complexes as the catalyst. The complexes are regarded as the real intermediates of these catalytic reactions or as the model compounds of the intermediates. Quantitative discussion on the homogeneous and heterogeneous catalysis requires thorough understanding of the organotransition metal chemistry. This class contains two parts. The early part focuses on fundamental bonding, structures, and chemical properties of the organotransition metal complexes. The latter part covers the synthetic organic reactions using transition metal compounds as the catalyst. It involves not only scope and limitation of the recent synthetic organic reactions using transition metal catalysts but also role of the reactions in synthesis of organic compounds, including drugs, fundamentals, and materials. A few recent topics of research of this field are also included.
The undergraduate students will attain basic concepts of organotransition metal chemistry and current trends in synthetic organic chemistry using transition metal complexes as the catalysts.
Course description and aims
By the end of this course, students will be able to:
1) Understand coordination bonds of organotransition metal complexes.
2) Explain the mechanism of reductive elimination, β-hydrogen elimination, and migratory insertion, and to mention relevance of the chemical properties of the organotransition metal complexes to homogeneous catalytic reactions.
3) Understand types and reaction mechanisms of homogeneous catalytic reactions such as hydrogenation, carbonylation, allylic substitution, cross-coupling reaction, and modern catalytic reactions.
Keywords
homogeneous catalysis, organotransition metal chemistry, cross-coupling reaction, carbonylation
Competencies
- Specialist skills
- Intercultural skills
- Communication skills
- Critical thinking skills
- Practical and/or problem-solving skills
Class flow
Simple quize is applied at the end of the class just for the students to check their understanding.
Course schedule/Objectives
| Course schedule | Objectives | |
|---|---|---|
| Class 1 | Basics of transition metal complexes. Structures of transition metal complexes and ligands. | Explain the formal oxidation numbers of transition metal complexes and typical ligands based on the covalent and ionic models |
| Class 2 | Synthetic reactions of alkyltransition metal complexes and their chemical properties. Oxidative addtition and reductive elimination. | Explain preparation and structures of major alkyltransition metal complexes, oxidative addition, and reductive elimination |
| Class 3 | Bonding of olefin complexes and carbonyl complexes. Insertion of olefin and of carbonyl ligands into a metal-alkyl bond, β-hydrogen elimination, and decarbonylation. | Explain π-back donation of olefin, carbonyl complexes、migratory insertion of olefin and carbonyl ligands into a M-C bond, and elimination of the small molecules. |
| Class 4 | Bonding and chemical properties of π-allyl complex and carbene complex. Stoichiometric allylation and metathesis reactions. Properties of NHC ligands. | Explain difference of σ- and π-allyl complexes, their dynamic behavior, and reactivity of carbene complexes. |
| Class 5 | Homogenous catalytic reactions (1) | Explain description of catalytic cycles on the basis of elementary reactions, principles and application of reactions of H2 and CO |
| Class 6 | Homogenous catalytic reactions (2) | Explain principles and application of cross-coupling reaction |
| Class 7 | Homogenous catalytic reactions (3) | Explain principles and application of allylic substitution reaction and modern catalytic reactions |
Study advice (preparation and review)
To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterwards (including assignments) for each class.
They should do so by referring to textbooks and other course material.
Textbook(s)
not applied
Reference books, course materials, etc.
Handout is delivered at every class
Evaluation methods and criteria
Score of mini-exam or final exam (100%).
Related courses
- Advanced Chemistry of Transition Metal Complexes II
Prerequisites
Organic chemistry and inorganic chemistry of undergraduate level are required.
Contact information (e-mail and phone) Notice : Please replace from ”[at]” to ”@”(half-width character).
Yoshiaki Shoji yshoji[at]res.titech.ac.jp
Office hours
Contact by e-mail in advance to schedule an appointment.
Other
It is inhibited to take both this class and CAP.T431"Advanced Organometallic Chemistry and Catalysis 1".