2024 Faculty Courses School of Materials and Chemical Technology Undergraduate major in Chemical Science and Engineering
Chemical Science and Engineering LaboratoryⅡ
- Academic unit or major
- Undergraduate major in Chemical Science and Engineering
- Instructor(s)
- Seiko Kimijima / Tetsuro Murahashi / Mina Okochi / Hideyuki Otsuka / Toshiro Takao / Akira Ohtomo / Takashi Ishizone / Masatoshi Kubouchi / Manabu Ihara / Kazuko Nakazono / Tsubasa Omoda / Kosuke Sato / Ryoyu Hifumi / Akira Takahashi / Miho Aizawa / Chihiro Homma / Takuto Soma / Yuuki Sugawara / Akimitsu Miyaji / Shogo Saito / Tatsuya Moriai / Keisuke Kameda / Masataka Oishi
- Class Format
- Experiment (Face-to-face)
- Media-enhanced courses
- -
- Day of week/Period
(Classrooms) - 5-8 Thu / 5-8 Fri
- Class
- -
- Course Code
- CAP.F206
- Number of credits
- 004
- Course offered
- 2024
- Offered quarter
- 3-4Q
- Syllabus updated
- Mar 17, 2025
- Language
- Japanese
Syllabus
Course overview and goals
[Description of the course]
In this course, the instructor will give instructions on basic tasks of chemical experiments for sophomore students who studied Chemical Science and Engineering Laboratory I (or Chemical Engineering and Industrial Chemistry Laboratories I a/b and I b/a), to cultivate their skills in experimental tasks and their understanding of organic chemistry, inorganic chemistry, analytical chemistry, and physical chemistry. From the viewpoint of a practical chemical industry education, the following six themes are set; (theme 1) “Aldehyde and ketone discrimination and nucleophilic addition” for learning a reaction using a Grignard reagent, which is a typical organic metal compound, (theme 2) “Synthesis of ε-Caprolactam and its ring-opening polymerization” for learning the preparation of nylon, which is a typical synthetic fiber, (theme 3) “Synthesis and spectroscopic analaysis of azo dye” for learning pigment synthesis as a model of dye industry, (theme 4) “Synthesis and composition analysis of ferrite”, for learning synthesis of the magnetic material which was invented in our institute and has been studied as advanced materials today, and demonstration of magnetic recording, (theme 5) "Homogeneous catalytic reactions" to learn the mechanism and reaction rate of H2O2 decomposition in homogeneous solutions containing catalysts, and (theme 6) "Measurement of electrical conductivity" to learn dissociation degree of electrolyte in solution and law of the independent migration of ions. Students will take three of these six themes in each quarter.
[Aim of the course] To understand the connection of basic chemistry to material society, it is essential to deeply examine the experimental results obtained by synthesis reaction through analyses and comprehension. One must learn the fundamental tasks with certainty and then approach the experiments with the underlying principles of reactions and safety. In this experiment, students first learn the essentials of fundamental tasks in a lecture and experimental presentation. Then, they practice the fundamental tasks while going through the six themes. Examinations of basic knowledge and practical thinking as well as writing experimental reports for each theme will enable the students to acquire correct synthetic and analytical techniques and to cultivate discussion skills.
Course description and aims
At the end of this course, students will be able to:
1) apply basic fundamental tasks according to the experimental objectives of each theme.
2) complete a general style of the experimental report including results, discussions, and survey details.
3) explain the basic concepts and measurement principles related to each theme and their applications.
4) acquire systematic knowledge from experiments and develop a plan for a safe and productive chemical experiment.
Keywords
(Theme 1. Aldehyde and ketone discrimination and nucleophilic addition) nucleophilic addition, reduction, functional group discrimination, organometalic chemistry, gas chromatography
(Theme 2.ε-Caprolactam and its ring-opening polymerization) oximation reaction, Beckmann rearrangement, recrystallization, ring-opening polymerization, 6-nylon
(Theme 3. Synthesis and spectroscopic analysis of azo dye) azo dye, diazotization reaction, diazo coupling, Lambert-Beer law, dyeing, ultraviolet and visible absorption spectrum, fiber (natural/artificial polymer),
(Theme 4. Synthesis and composition analysis of ferrite) ferrite, ellingham diagram, control of non-stoichiometry, magnetic susceptibility, thermogravimetric analysis, density measurement
(Theme 5. Homogeneous catalytic reactions) reaction kinetics, homogeneous catalytic reaction, reaction rate constant, reaction order, Arrhenius equation
(Theme 6. Measurement of electrical conductivity) ionic conduction, conductivity, electrolytes, Kohlrausch's law, chemical equilibrium
Competencies
- Specialist skills
- Intercultural skills
- Communication skills
- Critical thinking skills
- Practical and/or problem-solving skills
Class flow
In this course, students are divided into groups to learn the following six experiments in turn: (theme 1) Aldehyde and ketone discrimination and nucleophilic addition, (theme 2) Synthesis of ε-caprolactam and ring-opening polymerization,(theme 3) Synthesis and spectroscopic analysis of azo dye, (theme 4) Synthesis and composition analysis of ferrite, either (theme 5) Homogeneous catalytic reactions, and (theme 6) Measurement of electrical conductivity. On the last day, exercise problems and interpretation of the answers will be given to assess the students’ level of understanding.
Course schedule/Objectives
| Course schedule | Objectives | |
|---|---|---|
| Class 1 | Guidance on experimental outline and preparation for the experiments | Understand the outline of experiments and basic experimental operations, and draw up experimental plans. |
| Class 2 | Aldehyde and ketone discrimination and nucleophilic addition I Characterization of carbonyl functional groups | Characterize carbonyl functional groups. |
| Class 3 | Aldehyde and ketone discrimination and nucleophilic addition II Nucleophilic addition, reduction | Synthesize alcohols by using hydride reagents. |
| Class 4 | Aldehyde and ketone discrimination and nucleophilic addition III Distillation under reduced pressure, analysis | Purify the products by distillation and analyze the isolated compounds. |
| Class 5 | Aldehyde and ketone discrimination and nucleophilic addition IV Nucleophilic addition - introduction to organometallic chemistry | Synthesize alcohols by the Grignard reagents. |
| Class 6 | Synthesis ofε-Caprolactam and its ring-opening polymerization I Nucleophilic addition | Synthesize oximes from carbonyl compounds. |
| Class 7 | Synthesis ofε-Caprolactam and its ring-opening polymerization II Beckmann rearrangement | Synthesize amides by Beckmann rearrangement. |
| Class 8 | Synthesis ofε-Caprolactam and its ring-opening polymerization III: recrystallization | Purify ε-Caprolactam by recrystallization. |
| Class 9 | Synthesis ofε-Caprolactam and its ring-opening polymerization IV: ring-opening polymerization | Prepare 6-nylon by ring-opening polymerization. |
| Class 10 | Synthesis and spectroscopic analysis of azo dye I: synthesis of acid azo dye | Explain diazotization reaction and diazo coupling. |
| Class 11 | Synthesis and spectroscopic analysis of azo dye II: analysis of acid azo dye by thin layer chromatography and dyeing test | Evaluate the purity of the product. Explain the mechanism of fiber dyeing with acid azo dye. |
| Class 12 | Synthesis and spectroscopic analysis of azo dye III: UV/Vis absorption spectrum measurement | Measure the UV-visible absorption spectrum of a solution of acid azo dye. |
| Class 13 | Synthesis and spectroscopic analysis of azo dye IV: determination of λmax and εmax of acid azo dye | Determine the maximum absorption wavelength (λmax) and molar absorption coefficient (εmax) of acid azo dye from UV/Vis spectra. |
| Class 14 | Synthesis and composition analysis of ferrite I: wet synthesis (filtration under reduced pressure, drying) | Prepare metal oxide by wet synthesis. |
| Class 15 | Synthesis and composition analysis of ferrite II: dry synthesis (control of oxygen non-stoichiometry) | Prepare metal oxide by dry synthesis. |
| Class 16 | Synthesis and composition analysis of ferrite III: composition analysis (titration analysis, thermogravimetric analysis, and density measurement) | Evaluate oxidation number by titration analysis. Evaluate oxidation number by thermogravimetric analysis. Measure the density of a solid. |
| Class 17 | Synthesis and composition analysis of ferrite IV: measurement of physical properties (measurement of magnetic susceptibility, magnetic recording) | Explain magnetic recording. |
| Class 18 | Homogeneous catalytic reaction I. Method for measuring reaction rates and preparation of solutions | Perform titration of a H2O2 solution using KMnO4 |
| Class 19 | Homogeneous catalytic reaction II. Decomposition reaction of hydrogen peroxide | Learn about H2O2 degradation mechanism and kinetics in homogeneous solution containing KI as a catalyst. |
| Class 20 | Homogeneous catalytic reaction III. Decomposition reaction of hydrogen peroxide (Effect of temperature) | Explore the effect of temperature on H2O2 degradation kinetics in homogeneous solution containing KI as a catalyst. |
| Class 21 | Homogeneous catalytic reaction IV. Analysis and discussion of the experimental data | Analyze the kinetics of H2O2 degradation based on the results obtained from the experiments. |
| Class 22 | Measurement of electrical conductivity I. Description of measurement method and assembly of the measuring circuit | Learn about cell constant and how to build a bridge circuit. |
| Class 23 | Measurement of electrical conductivity II. Measurement of Infinite dilution molar conductivity in strong electrolyte solution | Acquire skills for measuring electrical resistance with high accuracy. |
| Class 24 | Measurement of electrical conductivity III. Discussion of Infinite dilution molar conductivity based on the law of independent ionic migration | Learn about how to get an infinite dilution molar conductivity and understand the law of independent ionic migration. |
| Class 25 | Measurement of electrical conductivity IV. Conductivity measurement of weak electrolyte solutions | Understand the degree of dissociation for weak electrolyte solutions. |
| Class 26 | Exercise problems to assess the students’ level of understanding and interpretation of the answers | Use the exercise problems to better understand the topics covered, and evaluate one’s own progress. |
Study advice (preparation and review)
To enhance effective learning, students are encouraged to spend a certain length of time outside of class on preparation and review (including for assignments), as specified by the Tokyo Institute of Technology Rules on Undergraduate Learning (東京工業大学学修規程) and the Tokyo Institute of Technology Rules on Graduate Learning (東京工業大学大学院学修規程), for each class.
They should do so by referring to textbooks and other course material.
Textbook(s)
Textbook for the Chemical Science and Engineering Laboratory II (In Japanese), edited by committee for the chemical science and engineering laboratory (Department of Chemical Science and Engineering, School of Materials and Chemical Technology, Tokyo Institute of Technology). This textbook will be available in a co-op store.
Reference books, course materials, etc.
化学同人編集部著 『続 実験を安全に行うために―基本操作・基本測定編―』 第4版（化学同人）ISBN: 978-4-7598-1834-5
Evaluation methods and criteria
Full attendance and completion of all experiments are compulsory. Assessment is based on the experiment procedures including preparation for the experiments, and the status of submission and the quality of written reports. Students may fail to take credits if he/she repeatedly comes to class late or delay the submission of reports too often.
Related courses
- CAP.F205 ： Chemical Science and Engineering LaboratoryⅠ
- CAP.B201 ： Chemical Engineering and Industrial Chemistry Laboratory I a/b
- CAP.B202 ： Chemical Engineering and Industrial Chemistry Laboratory I b/a
- CAP.B203 ： Chemical Engineering and Industrial Chemistry Laboratory II a/b
- CAP.B204 ： Chemical Engineering and Industrial Chemistry Laboratory II b/a
Prerequisites
The prerequisite to take this course is that you have acquired the credits of "Chemical Science and Engineering Laboratory III" and "Chemical Science and Engineering Laboratory IV".
Without having acquired the credits of the above course, the credits of this course will not be counted as the necessary number of credits for graduation.
Students must have completed Chemical Science and Engineering Laboratory I (CAP.205), or both Chemical Engineering and Industrial Chemistry Laboratory I a/b (CAP.B201) and Chemical Engineering and Industrial Chemistry Laboratory I b/a (CAP.B202), or have equivalent knowledge.
Other
Related courses for each theme
CAP.O201 ： Organic Chemistry I(Alkanes, Alkenes, Alkynes)
CAP.O202 ： Organic Chemistry II(C-X)
CAP.O203 ： Organic Chemistry III(Benzene・C-O)
CAP.O204 ： Organic Chemistry IV（C=O・C≡N)
CAP.O301 ： Synthetic Organic Chemistry(C=0 Substitution・Condensation・C-N・Cyclic Reaction)
CAP.O303 ： Instrumental Analysis (Advanced Organic Molecular Spectrum Analysis)
CAP.Y202 ： Polymer Synthesis I (Step-Growth Polymerization)
CAP.Y203 ： Polymer Synthesis II (Chain Polymerizaiton)
CAP.N202 ： Inorganic Chemistry II (Structures of Solids and Chemical Reactions)
CAP.N304 ： Inorganic Solid Chemistry
CAP.H201 ： Physical Chemistry I (Thermodynamics)
CAP.H202 ： Physical Chemistry II (Chemical Equilibirum)
CAP.H203 ： Physical Chemistry III (Kinetics)
CAP.H301 ： Electrochemistry I (Basics)
CAP.H302 ： Electrochemistry II (Advanced)