2024 Faculty Courses School of Materials and Chemical Technology Undergraduate major in Chemical Science and Engineering
Organic Chemistry III(Benzene・C-O) B
- Academic unit or major
- Undergraduate major in Chemical Science and Engineering
- Instructor(s)
- Reiko Saito
- Class Format
- Lecture (Face-to-face)
- Media-enhanced courses
- -
- Day of week/Period
(Classrooms) - 3-4 Wed
- Class
- B
- Course Code
- CAP.O203
- Number of credits
- 100
- Course offered
- 2024
- Offered quarter
- 3Q
- Syllabus updated
- Mar 17, 2025
- Language
- Japanese
Syllabus
Course overview and goals
[Summary of the course] In this course, aromaticity, which is the origin of the properties of aromatic compounds, alcohols, phenols, ethers, and epoxides that contain oxygen atoms will be explained for the students who studied Organic Chemistry I (Alkanes) (Chemical Science and Engineering) and Organic Chemistry II (Alkenes).
[Aim of the course] Aromatic compounds are the compound group found widely in bioactive substances or an organic material, and it is extremely important to understand their properties, reactions, and synthesis. First, students understand the mechanism, substituent effect, and synthetic use of halogenation, nitration, Friedel-Crafts, and electrophilic substitution reactions of aromatic compounds. Next, students understand the property, synthesis, and reactions of alcohols/phenols, ethers/epoxides, thiols/sulfides.
Course description and aims
By the end of this course, students acquire the following abilities:
(1) Ability to explain the properties and reactivity of aromatic compounds, such as benzene.
(2) Ability to explain the properties and reactivity of alcohols and phenols, which are the compounds containing oxygen atoms.
(3) Ability to explain the properties and reactivity of thiols and sulfides, which are the compounds containing sulfur atoms.
(4) Ability to draw up a synthetic plan of a target compound, based on (1), (2), and (3) above.
Keywords
Benzene, aromaticity, electrophilic aromatic substitution, oxidation, reduction, alcohols, phenols, ethers, epoxides, thiols, sulfides
Competencies
- Specialist skills
- Intercultural skills
- Communication skills
- Critical thinking skills
- Practical and/or problem-solving skills
Class flow
This course will proceed in the following order: (1) the property of the compounds indicating the aromaticity, (2) electrophilic aromatic substitution reactions (appearance of reactivity and regioselectivity by the reaction mechanism / substituent effect), (3) properties, reactivity, and synthesis of alcohols / phenols / ethers / epoxides, (4) properties, reactivity, and synthesis of thiols / sulfides. In the last day, practice problems and interpretation of them will be carried out to check the level of understanding.
Course schedule/Objectives
| Course schedule | Objectives | |
|---|---|---|
| Class 1 | Benzene and aromaticity | Explain an enantiomer and optical activity. |
| Class 2 | Chemistry of benzene: Electrophilic aromatic substitution | Explain electrophilic aromatic substitution reactions. |
| Class 3 | Chemistry of benzene: Oxidation and reduction of aromatic compounds | Explain oxidation and reduction of aromatic compounds. |
| Class 4 | Alcohols and phenols: Property and synthesis | Explain property and synthesis of alcohols and phenols. |
| Class 5 | Alcohols and phenols: reaction | Explain reactions of alcohols and phenols. |
| Class 6 | Ethers and epoxides, and thiols and sulfides | Explain property, synthesis, and reactions of ethers and epoxides, and thiols and sulfides. |
| Class 7 | Practice problems and interpretation for confirming the level of understanding | Solve practice problems by accurate understanding of the above all lectures. |
Study advice (preparation and review)
To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterwards (including assignments) for each class.
They should do so by referring to textbooks and other course material.
Textbook(s)
McMurry Organic Chemistry, international edition of 8th revised edition (Cengage Learning) ISBN-13: 978-0840054531
Reference books, course materials, etc.
Study Guide with Student Solutions Manual for McMurry's Organic Chemistry, 9th Edition (Cengage Learning) ISBN-13: 978-1305080485
Evaluation methods and criteria
Practice problems and interpretation for confirming the level of understanding (85%), level of class participation (15%) (The level of class participation will be calculated by discussion, small examination and so on in the lecture.)
Related courses
- CAP.B211 ： Organic Chemistry I (Alkanes) (Chemical Science and Engineering)
- CAP.B212 ： Organic Chemistry II (Alkenes)
- CAP.A231 ： Advanced Organic Chemistry I (Organic Reactions)
- CAP.A332 ： Advanced Organic Chemistry II (Organic Reactions)
Prerequisites
The condition of the study will not be made, but it is desirable to study Organic Chemistry I (Alkanes) (Chemical Science and Engineering) and Organic Chemistry II (Alkenes).
Contact information (e-mail and phone) Notice : Please replace from ”[at]” to ”@”(half-width character).
tanaka.k.cg[at]m.titech.ac.jp (Ken Tanaka)
tokamoto[at]cap.mac.titech.ac.jp (Toshihiro Okamoto）
saito.r[at]cap.mac.titech.ac.jp (Reiko Saito）
Office hours
Make a reservation by an e-mail in advance.