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2024 Faculty Courses School of Materials and Chemical Technology Undergraduate major in Materials Science and Engineering

Organic Synthetic Chemistry C

Academic unit or major
Undergraduate major in Materials Science and Engineering
Instructor(s)
Teruaki Hayakawa
Class Format
Lecture (Face-to-face)
Media-enhanced courses
-
Day of week/Period
(Classrooms)
5-6 Thu
Class
-
Course Code
MAT.P316
Number of credits
100
Course offered
2024
Offered quarter
2Q
Syllabus updated
Mar 14, 2025
Language
Japanese

Syllabus

Course overview and goals

The goal is for students to learn basic knowledge of approaches to synthetic chemistry and synthesis methods for organic and polymeric materials.

Course description and aims

Molecular structure design based on fundamental concepts of organic synthetic chemistry is important for the development of organic and polymeric materials. The most suitable raw materials and reactive agents, and precise exploration of reaction pathways are necessary for creating high-performance, high-function materials from low-cost starting materials. The instructor in this course will introduce basic concepts of retrosynthesis chemistry as an approach to synthetic organic methods, with the goal of students learning diverse functional group transformation reactions and bond-forming methods.

Keywords

retrosynthesis, organic and polymeric material, functional group transformation, molecular design

Competencies

  • Specialist skills
  • Intercultural skills
  • Communication skills
  • Critical thinking skills
  • Practical and/or problem-solving skills

Class flow

The class will move forward in line with handout contents. Handouts are distributed as necessary at the beginning of class. The instructor will go over and review the content of the previous class at the start of class. The instructor will solve practice problems during class, supplementing careful explanations. It is recommended that students prepare and review before and after class based on handout materials.

Course schedule/Objectives

Course schedule Objectives
Class 1 An overview of organic synthesis Explain the purpose of the lecture and how to proceed.
Class 2 Basic concepts of the retrosynthesis for organic chemistry Understanding the concept of retrosynthesis in organic chemistry must be required.
Class 3 Retrosynthesis: alkyl halide Understanding the synthesis of alkyl halide based on the concept of retrosynthesis must be required. Students must be able to explain the importance of the points.
Class 4 Retrosynthesis: alcohol, ether, amine (1) Understanding the synthesis of alcohols based on the concept of retrosynthesis must be required. Students must be able to explain the importance of the points.
Class 5 Retrosynthesis: alcohol, ether, amine (2) Understanding the synthesis of amines based on the concept of retrosynthesis must be required. Students must be able to explain the importance of the points.
Class 6 Retrosynthesis: 1- and 2-substituted alcohols, amines Understand and explain the synthesis of 1- and 2-substituted alcohols and amines from the concept of retrosynthesis.
Class 7 Retrosynthesis: carboxylic acid and its derivatives Understanding the synthesis of carboxylic acid and its derivatives based on the concept of retrosynthesis must be required. Students must be able to explain the importance of the points.
Class 8 Summary: Exam Understand the structure and stability of Understand and explain the concept of retrosynthetic analysis and each reaction in a comprehensive manner.

Study advice (preparation and review)

To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterward (including assignments) for each class.
They should do so by referring to textbooks and other course material.

Textbook(s)

nothing special

Reference books, course materials, etc.

Hiroshi Takahashi, The concept of organic synthesis method, Sankyo Publishing, ISBN4-7827-0195-0
Organic Synthesis, Christine L. Willis, Martin Wills, Tokyo Kagaku Dojin, ISBN978-4-7598-0816-2

Evaluation methods and criteria

The grade is mainly evaluated based on the results of the term-end examination.

Related courses

  • MAT.P314 : Organic Synthetic Chemistry A
  • MAT.P315 : Organic Synthetic Chemistry B
  • MAT.P213 : Organic Chemistry (Reaction-A)
  • MAT.P214 : Organic Chemistry (Reaction-B)

Prerequisites

It is desired that students have taken Organic Synthetic Chemistry A, Organic Synthetic Chemistry B, Organic Chemistry (Reaction-A), and Organic Chemistry (Reaction-B).

Contact information (e-mail and phone) Notice : Please replace from ”[at]” to ”@”(half-width character).

hayakawa.t.ac[at]m.titech.ac.jp

Office hours

Instructor's office: South Bldg. 8, Rm 813, 8th Fl. Contact by e-mail in advance to schedule an appointment.