2024 Faculty Courses School of Science Department of Chemistry Graduate major in Chemistry
Advanced Organometallic Chemistry
- Academic unit or major
- Graduate major in Chemistry
- Instructor(s)
- Makoto Yamashita
- Class Format
- Lecture (Face-to-face)
- Media-enhanced courses
- -
- Day of week/Period
(Classrooms) - 3-4 Mon / 3-4 Thu
- Class
- -
- Course Code
- CHM.D433
- Number of credits
- 200
- Course offered
- 2024
- Offered quarter
- 3Q
- Syllabus updated
- Mar 14, 2025
- Language
- English
Syllabus
Course overview and goals
Fundamental aspects of organometallic compounds will be described first, and then application to synthetic organic reactions using these organometallic compounds will be presented. Initially, synthesis and reaction of main group organometallic compounds will be discussed. Then fundamental aspects of transition metal complexes on structure, oxidation state and ligands will be discussed. Then basic reactions of transition metal compounds will be shown, and application to various kinds of synthetic reactions such as coupling reaction, metathesis reaction, etc. will be presented. Students can obtain basic knowledge of organic reactions mediated or catalyzed by organometallic complexes.
Course description and aims
Understanding the structures, properties, and catalytic functions of organometallic compounds, and gaining the ability to make a research proposal by utilizing the knowledge obtained in this course
Keywords
Organometallic compound, Organic syntheis,
Competencies
- Specialist skills
- Intercultural skills
- Communication skills
- Critical thinking skills
- Practical and/or problem-solving skills
Class flow
Lectures will be based on the distributed handouts and their explanation with writing on them. At the end of the class, students have to solve problem sets related to the lecture.
Course schedule/Objectives
| Course schedule | Objectives | |
|---|---|---|
| Class 1 | Synthesis and reaction of organolithium and magnesium compounds | Exercise problems might be given in this class. |
| Class 2 | Synthesis and reaction of group 12 metal compounds | Exercise problems might be given in this class. |
| Class 3 | Synthesis and reaction of group 13 metal compounds | Exercise problems might be given in this class. |
| Class 4 | Synthesis and reaction of group 14 metal compounds | Exercise problems might be given in this class. |
| Class 5 | Fundamental aspect of organotransition metal complexes 1 (structure, oxidation state, ligand) | Exercise problems might be given in this class. |
| Class 6 | Fundamental aspect of organotransition metal complexes 2 (elementary reactions) | Exercise problems might be given in this class. |
| Class 7 | Reaction of alkene-coordinated transition metal complexes | Exercise problems might be given in this class. |
| Class 8 | Reaction of alkyne, diene, and arene-coordinated transition metal complexes | Exercise problems might be given in this class. |
| Class 9 | Reaction of allylmetal complexes | Exercise problems might be given in this class. |
| Class 10 | Reaction of organocopper complexes | Exercise problems might be given in this class. |
| Class 11 | Cross coupling reactions 1 | Exercise problems might be given in this class. |
| Class 12 | Cross coupling reactions 2 | Exercise problems might be given in this class. |
| Class 13 | Reaction of metal hydride complexes | Exercise problems might be given in this class. |
| Class 14 | Reaction of metal carbene complexes | Exercise problems might be given in this class. |
Study advice (preparation and review)
To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterwards (including assignments) for each class.
They should do so by referring to textbooks and other course material.
Textbook(s)
None
Lecture handout will be uploaded via T2SCHOLA.
Reference books, course materials, etc.
Hartwig: Organotransition Metal Chemistry: From Bonding to Catalysis (Univ Science Books)
Evaluation methods and criteria
Exercise problems, report, and final exam. Students' knowledge of organotransition metal chemistry along with its application to synthetic organic reactions, and their ability to apply them to problems will be assessed.
Related courses
- CHM.D401 ： Basic Concepts of Organic Chemistry I
- CHM.D402 ： Basic Concepts of Organic Chemistry II
Prerequisites
Expected to have basic knowledge of organic chemistry.