2023 Faculty Courses School of Materials and Chemical Technology Undergraduate major in Chemical Science and Engineering
Biochemical Engineering
- Academic unit or major
- Undergraduate major in Chemical Science and Engineering
- Instructor(s)
- Mina Okochi / Masayoshi Tanaka
- Class Format
- Lecture (Face-to-face)
- Media-enhanced courses
- -
- Day of week/Period
(Classrooms) - 3-4 Mon (S2-204(S221))
- Class
- -
- Course Code
- CAP.G301
- Number of credits
- 100
- Course offered
- 2023
- Offered quarter
- 1Q
- Syllabus updated
- Jul 8, 2025
- Language
- Japanese
Syllabus
Course overview and goals
This Bioprocess Engineering course is intended for 3rd year students and focuses on the use of biocatalysts in production and material transformation. The aims of this course are for students to gain fundamental knowledge of enzymes and microorganisms used as biocatalysts, and reaction kinetics and fermentation balance from an engineering perspective. Also, process operation of bioreactor using microorganisms and sterilization process are explained.
Course description and aims
By the end of this course, students will be able to:
1) explain the mechanism of genetic information transfer and protein expression.
2) explain characteristics of enzyme and its reaction kinetics
3) explain characteristics of microbial fermentation and its general kinetics
4) understand bioreactor design and its operation
5) explain sterilization methods and set treatment conditions
Keywords
Genetic engineering, Microorganism, Enzyme, Metabolism, Reaction kinetics, Fermentation balance, Bioreactor
Competencies
- Specialist skills
- Intercultural skills
- Communication skills
- Critical thinking skills
- Practical and/or problem-solving skills
Class flow
Toward the end of class, students are given exercise problems related to what is taught in the class.
Course schedule/Objectives
| Course schedule | Objectives | |
|---|---|---|
| Class 1 | Molecules that makeup living organisms | Understand the roles of molecules (carbohydrates, amino acids, proteins, nucleic acids, lipids, vitamins, etc.) that makeup living organisms |
| Class 2 | Genetic engineering | Understand the transfer of genetic information (including DNA replication, transcription, and translation), etc., and be able to explain basic genetic engineering techniques. |
| Class 3 | Regulation of transcription and microbial production of target proteins | Understand the mechanism of transcriptional regulation and be able to explain the mechanism of induction of target proteinexpressions in microorganisms. |
| Class 4 | Enzyme characteristics and processes | Explain characteristics of enzyme and its reaction kinetics |
| Class 5 | Microbial fermentation, fermentation balance, and growth kinetics | Explain fermentation balance and growth kinetics |
| Class 6 | Bioreactor, continuous culture | Explain characteristics of microbial fermentation using bioreactor and its operating condition |
| Class 7 | Sterilization | Explain sterilization methods and set treatment conditions |
Study advice (preparation and review)
To enhance effective learning, students are encouraged to spend approximately 30 minutes preparing for class and another 30 minutes reviewing class content afterward (including assignments) for each class.
They should do so by referring to textbooks and other course material.
Textbook(s)
Kenji Hashimoto. Hannou Kougaku. Tokyo: Baifukan. ISBN-10: 4563045187.
Reference books, course materials, etc.
Hajime Unno, Kazuhiro Nakanishi eds. Yasunori Tanji, Masanao Imai, Masafumi Yohda, Hiroyasu Ogino. "Biological Chemical Engineering" 3rd edition, Tokyo:Kodansha, ISBN 978-4-06-139831-3.
Takeshi Kobayashi, Hiroyuki Honda. "Biological Chemical Engineering" Tokyo:Tokyo Kagaku Dojin. ISBN 4-8079-1427-8.
Evaluation methods and criteria
Exercise problems (50%), report (50%)
Related courses
- CAP.C207 ： Introduction to Biotechnology
- CAP.C206 ： Chemical Reaction Engineering I (Homogeneous System)
- ZUJ.C301 ： Introduction to Biochemical Process
- CAP.C306 ： Chemical Reaction Engineering II (Heterogeneous System)
Prerequisites
None