2020 Faculty Courses School of Science Department of Chemistry Graduate major in Chemistry
Basic Concepts of Organic Chemistry
- Academic unit or major
- Graduate major in Chemistry
- Instructor(s)
- Ken Ohmori / Kei Goto
- Class Format
- Lecture (Zoom)
- Media-enhanced courses
- -
- Day of week/Period
(Classrooms) - 3-4 Mon (H135) / 3-4 Thu (H135)
- Class
- -
- Course Code
- CHM.D401
- Number of credits
- 200
- Course offered
- 2020
- Offered quarter
- 1Q
- Syllabus updated
- Jul 10, 2025
- Language
- English
Syllabus
Course overview and goals
The course is designed to understand stereoelectronic effects to understand general reactivity of organic compounds and stereoselectivity in organic reactions. This course also focuses on the fundamental aspects of the intermolecular interactions associated with organic molecules as well as the structures of supramolecular assemblies.
Course description and aims
Students will able to explain basic facts related to the stereochemistry of organic compounds and the stereoselectivity of reactions such as the stereoelectronic effect and molecular orbital theory. Students will also gain an understanding of the role of intermolecular interactions on the structures and reactions of organic compounds.
Keywords
Stereoelectronic effect, Stereochemistry, Intermolecular interaction, Supramolecular chemistry
Competencies
- Specialist skills
- Intercultural skills
- Communication skills
- Critical thinking skills
- Practical and/or problem-solving skills
Class flow
Most course contents and topics are given by board writing.
Course schedule/Objectives
| Course schedule | Objectives | |
|---|---|---|
| Class 1 | Stereoelectronic effects: Felkin–Anh model, Cieplak model, Bürgi–Dunitz trajectory | Exercise problems might be given in this class. |
| Class 2 | Stereoelectronic effects: conformation and reactivity of cyclohexane derivative, A-value | Exercise problems might be given in this class. |
| Class 3 | Stereoelectronic effects: anomeric effect | Exercise problems might be given in this class. |
| Class 4 | Stereoelectronic effects: Gauche effect | Exercise problems might be given in this class. |
| Class 5 | Stereoelectronic effects: Baldwin's rule | Exercise problems might be given in this class. |
| Class 6 | Stereoelectronic effects: Bredt rule, reaction of small ring-sized compounds | Exercise problems might be given in this class. |
| Class 7 | Stereoelectronic effects: other topics and exercise problems | Exercise problems might be given in this class. |
| Class 8 | Basic concepts of intermolecular interactions and supramolecular chemistry | Exercise problems might be given in this class. |
| Class 9 | Properties and classification of intermolecular interactions | Exercise problems might be given in this class. |
| Class 10 | Electrostatic interaction, van der Waals force, donor-acceptor interaction | Exercise problems might be given in this class. |
| Class 11 | Hydrogen bonding, hydrophobic effect | Exercise problems might be given in this class. |
| Class 12 | Concept of preorganization | Exercise problems might be given in this class. |
| Class 13 | Self-assembly | Exercise problems might be given in this class. |
| Class 14 | Intermolecular interactions in supramolecular catalysis | Exercise problems might be given in this class. |
Study advice (preparation and review)
To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterwards (including assignments) for each class.
They should do so by referring to textbooks and other course material.
Textbook(s)
None
Reference books, course materials, etc.
For stereoelectronic effects
1) Stereoelectronic Effects, A. J. Kirby, Oxford University Press; 2) Stereochemistry in Organic Compounds, E. L. Eliel and S. H. Wilen, Wiley;
For pericyclic reactions
3) Pericyclic Reactions, I. Fleming, Oxford University Press.
Evaluation methods and criteria
"Final exam. Students' understanding of stereoelectronic effects and pericyclic reactions and their ability to apply them to problems will be assessed. "
Related courses
- CHM.D201 ： Organic Chemistry I
- CHM.D202 ： Organic Chemistry II
- CHM.D301 ： Organic Chemistry III
- CHM.D331 ： Organic Synthesis
- CHM.D333 ： Organic Reactions
Prerequisites
Have basic knowledge of organic chemistry